ETD Collection for Thomas Jefferson University

Dissertations & Theses from 2007

Pao, Christina S (2007) Mechanism of G protein-coupled receptor kinase binding and activation by G protein-coupled receptors

{ top }

Dissertations & Theses from 2005

Duffy, Kevin T (2005) Perturbation of oncogenic orthologs in zebrafish

{ top }

Dissertations & Theses from 2000

Halak, Brian Keith (2000) The role of interleukin-10 in immune escape by a murine transitional cell carcinoma

Woodward, Wendy Ann (2000) Regulation of embryonic limb mesenchymal chondrogenesis: Cell adhesion and Wnt signaling

{ top }

Dissertations & Theses from 1999

Antonyak, Marc A (1999) Elevated JNK activation contributes to transformation and resistance to apoptosis in an in vitro model of transformation and in primary brain tumors

Carman, Christopher Vincent (1999) Characterization of novel G protein-coupled receptor kinase interactions and functions

Chepenik, Lara Gayle (1999) Mechanisms by which the cellular protein, Pur-alpha, and HIV-1 Tat mediate transcription of viral genes

Choi, Eugene Jinkyu (1999) Adhesion molecules mediate the ability of human polymorphonuclear neutrophils to proteolytically penetrate a basement membrane-like barrier

Edling, Andrea Elizabeth (1999) The effect of small molecular inhibitors of CD4 on experimental allergic encephalomyelitis

Goodman, Oscar Baylin (1999) Clathrin lattice assembly and adaptor recruitment in receptor-mediated endocytosis

Gradia, Scott David (1999) Signaling human mismatch repair by the formation of ahMSH2-hMSH6 sliding DNA clamp

Haltiwanger, Brett Maher (1999) Characterization of a DNA base excision repair pathway in the malaria parasite Plasmodium falciparum: From RIPs to repair

Jiang, An (1999) The construction and applications of cell-type-specific retroviral gene-transfer vectors derived from spleen necrosis virus: From in vitro to in vivo

Kang, Jason Jongho (1999) Apoptotic caspase activation in the yeast Saccharomyces cerevisiae

Kouba, David Jonathan (1999) Transcriptional regulation of the human alpha2(I) collagen (COL1A2) gene by tumor necrosis factor-alpha and interferon-gamma

Krupnick, Jason Garrett (1999) Molecular mechanisms of regulation of G protein-coupled receptor signaling by arrestins

Kundu, Mondira (1999) Mutual interactions between HIV-1 and the host cell cycle: Implications for the neuropathogenesis of ADC

Neary, Catherine Louise (1999) The role of the cytoskeleton in cell death

Reed, Charles Christopher (1999) Ligand recognition in mutant proteins

Safak, Mahmut (1999) A 23-base-pair sequence element and its role in JC virus gene transcription

Serio, Dawn Marie (1999) Novel HIV-1 therapeutic agents based on virion-targeted viral proteins

Shah, Asit K (1999) Effects of transforming growth factor beta-1 and bone morphogenetic protein-2 on osteoblasts at the bone-biomaterial interface

Steelman, Scott (1999) Members of the MEIS1 homeoprotein family are involved in binding the laminin B1 enhancer

Ukropec, Jon Alec (1999) Fluid shear stress-induced reorganization of adherens junctions in human endothelial cells

Wherry, Edward John (1999) The role of tripeptidyl peptidase II in MHC class I-restricted antigen processing and the effect of epitope density of CD8(+) T cell priming

{ top }

Dissertations & Theses from 1998

Bach, Tami Lee (1998) Identification of a novel interaction between the N-terminal domain of fibrin and VE-cadherin: Its role in angiogenesis

Bennett, Ian Moore (1998) Natural killer cell differentiation

Chianese-Bullock, Kimberly A (1998) Two MHC class II-restricted epitopes are processed in distinct endocytic compartments as a result of the acid-induced structural changes in a viral glycoprotein

Garcia, Ramon John (1998) Activation mechanisms of phospholipase D; an ethanol-metabolizing enzyme

Handler, Melissa (1998) Expression of the heparan sulfate proteoglycan perlecan during murine embryogenesis and tumorigenesis

Hershberger, Marcia E (1998) Placental 54 kDa Ca(2+) binding protein: Regulation of expression and function in trophoblast differentiation and calcium homeostasis

Howard-Claudio, Candace Michelle (1998) The effects ofRB2/p130 on tumorigenesis

Jerng, Henry Hungtao (1998) Mechanism of inactivation in brain potassium channels: Molecular gates and shutters

Lawe, Deirdre C (1998) The molecular and cellular characterization of Nck, an SH2/SH3 adaptor protein, in signal transduction

Lucas, Kimberly Anne (1998) Pathways of lipopolysaccharide-induced prostaglandin E(2) production in human microvascular endothelial cells

MacLachlan, Timothy Kenneth (1998) Characterization of thePITALRE/CDK9 and PISSLREcdc2-related kinases

Mendrola, Jeannine M (1998) Characterization of the receptor protein tyrosine phosphatase gamma gene product

Nossuli, Tareck Omar (1998) Effects of peroxynitrite, a reactive oxygen species, in myocardial reperfusion injury

Phiel, Christopher Jon (1998) Elucidation of the mechanism and pathways promoting intestinal smooth muscle cell differentiation

Rencic, Adrienne (1998) Molecular models for studying CNS associated tumors and dysmyelination

Taddeo, Frank J (1998) A comparative study of the modes of activation of protein kinase C

Trelka, Darin Patrick (1998) The ins and outs of macromolecular transport in malaria-infected erythrocytes

Veneziale, Robert William (1998) Organization of beta(1) integrin and N-cadherin mediated adhesion complexes during lens cell differentiation

Wagner, Marisa (1998) Genetic analysis of a mitogen-activated protein kinase required for spore morphogenesis in Saccharomyces cerevisiae

Wubah, Judith Afedua (1998) A model forp53 gene-teratogen interaction in early mouse embryos

Xu, Shi-Qiong (1998) Purification and identification of a growth factor that sustains the growth of fibroblasts null for the IGF-I receptor

{ top }

Dissertations & Theses from 1997

Brigandi, Richard A (1997) Antibody- and complement-mediated immunity to infective and autoinfective third stage larvae of Strongyloides stercoralis

Chen, Paul Chih-Hsueh (1997) Structural and functional analysis of the two human tumor necrosis factor receptors

Choksi, Swati (1997) Structure-based designed CD8 peptide analogs inhibit both in vitro and in vivo CD8(+) T cell responses

Denker, Andrew Evan (1997) Chondrogenic activity of transforming growth factor-beta(1) and bone morphogenetic protein-2 on multipotential mesenchymal cells

Deshmane, Sujata Praful (1997) Mechanisms underlying receptor-effector coupling of guanylyl cyclase C

Engelhard, Andrew G (1997) The role of the B-myb gene in differentiation

Evanko, Daniel Stephen (1997) Characterization of the human beta(1)-adrenergic receptor gene and its transcriptional regulation

Finnegan, Alysia Argeson (1997) Molecular characterization of the hypervariable yellow(A(hvy)) allele at the murine agouti locus and investigation of factors influencing phenotypic variability

Gersh, Meryl Hope (1997) The phenotypic mapping of the cat-like cry observed in the cri-du-chat syndrome and molecular characterization of the proposed critical region

Haas, Andrew Robert (1997) Chondrogenic induction by bone morphogenetic protein-2: Involvement of N-cadherin-associated functions

Hall, James Perry (1997) Investigations into mitogen-activated protein (MAP) kinase signal transduction pathways in Saccharomyces cerevisiae

Jena, Nilamani (1997) Structure-function analysis of BCL2(alpha) and characterization of BMP-7 null mice

Koblish, Michael (1997) Development of a murine model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) susceptibility for quantitative trait locus mapping

Koch, Ute (1997) Inhibition of bone marrow and skin graft rejection by a synthetic CD4-CDR3 peptide analog in murine transplantation models

Limardo, Maria Isabel (1997) Molecular genetics of the 180-kDa bullous pemphigoid antigen (BPAG2/COL17A1), a transmembrane protein of the basement membrane zone of the stratifying squamous epithelia

Loudon, Robert Peter (1997) Expression and characterization of the G protein-coupled receptor kinase GRK6

MacPhee-Pellini, Melina (1997) Secretory phospholipase A2: A candidate for the MOM1 locus, a major modifier of APC(Min)-induced intestinal neoplasia

Marini, Joseph C (1997) A CD4-CDER3 peptide analog inhibits both primary and secondary CD4T cell responses in experimental allergic encephalomyelitis

Martinez, Robert Vincent P (1997) Cloning and characterization of the DR-nm23 gene and its associated product, a novel member of thenm23 gene family

Moskow, John Joseph (1997) Identification and characterization of Meis1, a common site of viral integration involved in murine myeloid leukemia

Parkinson, Scott James (1997) Adenine nucleotide regulation of receptor guanylyl cyclases: Application to interrupt Escherichia coli heat-stable entertoxin-dependent signalling mediating secretory diarrhea

Raj, Ganesh Venkataram (1997) The molecular pathogenesis of demyelination and CNS tumors induced by the neurotropic papovavirus, JCV

Sang, Nianli (1997) Characterization of the transcriptional regulatory functions of the transforming region of the adenovirus E1A oncoprotein

Sell, Leslie Jean (1997) The molecular characterization of chromosome 18 abnormalities associated with specific phenotypes

Slavinsky, Christopher W (1997) Characterization and analysis of the murine cartilage oligomeric matrix protein (COMP) gene

Strathdee, Gordon Ronald (1997) Molecular and cytogenetic analysis of the 18q-syndrome

Thiyagarajan, Manimekalai Mohanasundari (1997) Characterization of Ustilago maydis topoisomerase I: Purification, cloning, biochemical and kinetic analysis

Victoria, Teresa (1997) Molecular characterization of the canine model for globoid cell leukodystrophy (Krabbe disease) and study of the effects of human polymorphisms on the activity of murine galactocerebrosidase

Yuan, Constance Miao-Leng (1997) The human COL1A1/COL2A1 chimeric gene in transgenic mice: Analysis of themRNA expression and the apparent inhibition of translation from the construct

{ top }

Dissertations & Theses from 1996

Basu, Soumitra (1996) Cellular pharmacology of oligonucleotide analogs

Bullock, Timothy Nicholas James (1996) MHC class I-restricted cryptic epitopes: Their production and immunogenicity

Chen, Nancie Nien-Tsyr (1996) Identification and characterization of cellular proteins regulating transcription of human neurotropic virus, JCV

Connelly, Patrick Raymond (1996) Retinoid signaling and cell cycle regulation during murine palate development

Earley, James Joseph (1996) High-throughput DNA sequence analysis for thr investigation of genetic diseases by the candidate gene approach

Hazel, Betsy Ann (1996) Hydroquinone, a major bone marrow metabolite of benzene, induces granulopoiesis in a mouse model: Possible role in benzene-induced acute myelogenous leukemia

Hill, Jason Eric (1996) Partial analysis of sequences expressed by human osteoblasts in vitro using differential display-PCR (DD-PCR)

Megonigal, Maureen D (1996) Mutant DNA topoisomerase I-induced lethality in Saccharomyces cerevisiae

Mylet, Johanna C (1996) The role of RAD1 in repeat-mediated double strand break repair of variable number tandem repeats (VNTRs) in Saccharomyces cerevisiae

Reardon, Brian James (1996) The molecular and genetic characterization of the DAT1 gene product of Saccharomyces cerevisiae

Rock, Matthew James (1996) Molecular genetic analysis of N-cadherin structure and function

{ top }

Dissertations & Theses from 1994

Liddell, Rebecca Ann (1994) Analysis of isoactin gene expression during normal and abnormal gastrointestinal smooth muscle development

{ top }

Dissertations & Theses from 1984

TSAY, BEELEIN LIN (1984) REGULATION OF MURINE RESPONSES TO THE KNOWN SEQUENCE POLYMER POLY (L-TYROSINE- L-GLUTAMIC ACID- L-ALANINE-GLYCINE)

{ top }

Dissertations & Theses from 1983

ELLIS, JOHN SIDNEY (1983) SYNTHESIS, CHARACTERIZATION AND IMMUNOLOGICAL STUDIES OF SIX KNOWN-SEQUENCE POLYMERS CONTAINING TYROSINE, GLUTAMIC ACID, ALANINE, AND GLYCINE