Minimal exposure intra-arterial chemotherapy for children with retinoblastoma and 13q syndrome.
Document Type
Article
Publication Date
10-3-2016
Abstract
Two infants with retinoblastoma and 13q syndrome with multiorgan system anomalies were treated with targeted intra-arterial chemotherapy (IAC) using one-to-three cycles of melphalan 5 mg to avoid systemic chemotherapeutic side effects. Both patients showed good response, with tumor control and no systemic chemotherapy side effects. Of the treatment modalities currently available, IAC may represent an optimal balance between tumor extermination and adverse drug reactions in this patient population with classically reduced multiorgan reserve.
Recommended Citation
Dillon, Alexander B; Douglass, Alexzandra; Jabbour, Pascal MD; and Shields, Carol L, "Minimal exposure intra-arterial chemotherapy for children with retinoblastoma and 13q syndrome." (2016). Wills Eye Hospital Papers. Paper 63.
https://jdc.jefferson.edu/willsfp/63
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 License.
PubMed ID
27843232
Comments
This article has been peer reviewed. It was published in: Oman journal of ophthalmology.
Volume 9, Issue 3, October 2016, Pages 164-166.
The published version is available at DOI: 10.4103/0974-620X.192278
Copyright © 2016 Oman Ophthalmic Society
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