Document Type
Response or Comment
Publication Date
3-6-2026
Abstract
PURPOSE: To discuss the recent evidence that Janus kinase (JAK) inhibitors can cause viral retinitis.
METHODS: A commentary on the case report in this issue and a review of cases in the literature.
RESULTS: A total of 6 cases have now been reported of cytomegalovirus retinitis associated with Jak inhibitors. Additionally, there was a case of bilateral toxoplasma retinitis and a case of herpetic scleritis.
DISCUSSION: It is important to be aware of the potential blinding complications associated with JAK inhibitors and if the patient complains of acute vision loss and/or floaters, the patient should be emergently referred to a retina specialist.
Recommended Citation
Pulido, Jose S.; Mano, Fukutaro; Casella, Marcello; and Ishida, Susumu, "Infectious Retinitis Associated With JAK Inhibitors: The Ongoing Duality of JAK Inhibitors" (2026). Wills Eye Hospital Papers. Paper 291.
https://jdc.jefferson.edu/willsfp/291
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
PubMed ID
41792858
Language
English
Included in
Chemical Actions and Uses Commons, Chemical and Pharmacologic Phenomena Commons, Eye Diseases Commons, Ophthalmology Commons
Comments
This article is the author’s final published version in International Journal of Retina and Vitreous, Volume 12, Issue 1, 2026, Article number 40.
The published version is available at https://doi.org/10.1186/s40942-026-00823-4. Copyright © The Author(s) 2026.