Document Type
Article
Publication Date
12-15-2025
Abstract
AIM AND BACKGROUND:To compare postoperative intraocular pressure (IOP) spikes and 1-year surgical success among goniotomy procedures: Kahook Dual Blade (KDB), OMNI, bent ab interno needle goniotomy (BANG), and gonioscopy-assisted transluminal trabeculotomy (GATT).
MATERIALS AND METHODS: This single-center, retrospective chart review included glaucoma patients ≥18 years, who underwent goniotomy from January 2021 to December 2022 with ≥3 months of follow-up. Primary outcomes were IOP spikes (≥10 mm Hg increase within 3 months) and 12-month surgical success (≥20% IOP and/or ≥1 medication reduction without further surgery). Secondary outcomes included IOP and medication changes.
RESULTS: Among 247 eyes (107 KDB, 63 OMNI, 77 BANG; all with phacoemulsification), IOP spikes occurred in 13.0% with no difference between groups (p = 0.900). Spikes were more common in severe glaucoma and associated with failure (p = 0.041), postoperative interventions (p < 0.001), and reoperation (p = 0.026). At 12 months (n = 164), 68.9% achieved success with no difference between procedures (p = 0.972). Lower baseline IOP, open-angle glaucoma (OAG), and IOP spikes predicted failure. GATT eyes (n = 39, mostly standalone) had different baseline characteristics, were excluded from main analysis, but showed similar success (79.3%) with greater IOP and medication reduction.
CONCLUSION: Kahook Dual Blade, OMNI, and BANG with phacoemulsification had comparable 1-year safety and efficacy. IOP spikes increase the risk of failure and reoperation, especially in severe glaucoma. GATT showed favorable outcomes when performed standalone.
CLINICAL SIGNIFICANCE: Choice among KDB, OMNI, and BANG can be individualized without compromising outcomes. Monitoring for IOP spikes is crucial in high-risk eyes. Standalone GATT offers strong results when cataract surgery is not needed.
HOW TO CITE THIS ARTICLE: Shalaby WS, Chang SL, Yu J, et al. Impact of Postoperative Intraocular Pressure Spikes on Outcomes Following Goniotomy: A Comparative Study of Surgical Techniques. J Curr Glaucoma Pract 2025;19(4):186–198.
Recommended Citation
Shalaby, Wesam S.; Chang, Steven L.; Yu, Julia; Horan, Teresa; Shah, Sagar; Hallaj, Shahin; Moster, Marlene; Razeghinejad, Reza; Lee, Daniel; Pro, Michael; Shukla, Aakriti; Huang, Ping; Myers, Jonathan S.; Xia, Tina; and Amarasekera, Dilru, "Impact of Postoperative Intraocular Pressure Spikes on Outcomes Following Goniotomy: A Comparative Study of Surgical Techniques" (2025). Wills Eye Hospital Papers. Paper 288.
https://jdc.jefferson.edu/willsfp/288
Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License
PubMed ID
41523173
Language
English
Included in
Health Services Research Commons, Musculoskeletal, Neural, and Ocular Physiology Commons, Ophthalmology Commons


Comments
This article is the author’s final published version in Journal of Current Glaucoma Practice, Volume 19, Issue 4, 2025, Pages 186-198.
The published version is available at https://doi.org10.5005/jp-journals-10078-1498. Copyright © The Author(s) 2025.