Document Type

Article

Publication Date

11-25-2025

Comments

This article is the author’s final published version in Journal of Ophthalmic Inflammation and Infection, Volume 15, Issue 1, 2025, Article number 89.

The published version is available at https://doi.org/10.1186/s12348-025-00547-w. Copyright © The Author(s) 2025.

Abstract

BACKGROUND: To describe the clinical features and management of three cases of bilateral endogenous fungal endophthalmitis following elective surgical abortion performed at the same outpatient surgical center.

METHODS: Case series.

OBSERVATIONS: Three immunocompetent women presented with vision loss days to weeks following elective surgical abortions performed at a single outpatient clinic. Initial visual acuities ranged from 20/20 to 20/300. Fundoscopic examination revealed multiple white round chorioretinal lesions with vitreous infiltration bilaterally in all three patients. Vitreous tap samples were obtained for culture and broad-spectrum intravitreal antimicrobials were administered. Despite negative cultures and systemic workup, the clinical presentation was consistent with fungal endophthalmitis. All patients received systemic and intravitreal antifungal therapy, leading to gradual resolution of lesions and improvement of visual acuity to 20/25 or better in all eyes.

CONCLUSIONS: This cases series represents the first reported cluster of endogenous fungal endophthalmitis following surgical abortion. Prompt recognition and treatment with intravitreal and systemic antifungals can result in favorable outcomes. The findings highlight the importance of stringent sterilization protocols in outpatient surgical settings and the need for heighted clinical suspicion in similar presentations.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

PubMed ID

41288891

Language

English

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