The Role of HIF1-Alpha in Regulating Carbonic Anhydrases within the Nucleus Pulposus

Authors

Philip Batista, MD, Thomas Jefferson UniversityFollow
Makarand V. Risbud, PhD, Department of Orthopaedic Surgery, Thomas Jefferson UniversityFollow

Document Type

Presentation

Presentation Date

5-29-2014

Abstract

Hypotheses:

Carbonic anhydrases plays an essential role in maintaining the homeostasis of the disc microenvironment due to its hypoxic nature.

HIF1-alpha plays a crucial role in CA regulation within NP cells and as a result disc degeneration may be related to inappropriate CA regulation.

Presentation: 12 minutes

Recommended Citation

Batista, MD, Philip and Risbud, PhD, Makarand V., "The Role of HIF1-Alpha in Regulating Carbonic Anhydrases within the Nucleus Pulposus" (2014). Department of Surgery Resident Research Day. Paper 3.
https://jdc.jefferson.edu/surresday/3