The burden of breast cancer in Italy: mastectomies and quadrantectomies performed between 2001 and 2008 based on nationwide hospital discharge records.

Authors

• Prisco Piscitelli, University of Florence, Viale Pieraccini 18, Florence
• Maddalena Barba, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome
• Massimo Crespi, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome
• Massimo Di Maio, Local Health Authority of Naples (ASL NA1), Centro piazza Nazionale 95, Naples
• Antonio Santoriello, Second University of Naples, Via Sergio Pansini, Naples
• Massiliamo D'Aiuto, National Cancer Institute G. Pascale Foundation, Via Mariano Semmola, Naples
• Alfredo Fucito, National Cancer Institute G. Pascale Foundation, Via Mariano Semmola, Naples
• Arturo Losco, Local Health Authority Salerno, via Nizza 146, Salerno
• Francesca Pentimalli, National Cancer Institute G. Pascale Foundation - Cancer Research Center, Via Ammiraglio Bianco, Mercogliano, Avellino
• Pasquale Maranta, Piazza Pianciani 5, Spoleto-Perugia, 06049, Italy
• Giovanna Chitano, Euro Mediterranean Biomedical Institute (ISBEM) Research Centre, Via Reali di Bulgaria, Brindisi, Mesagne,
• Alberto Argentiero, Euro Mediterranean Biomedical Institute (ISBEM) Research Centre, Via Reali di Bulgaria, Brindisi, Mesagne,
• Cosimo Neglia, Euro Mediterranean Biomedical Institute (ISBEM) Research Centre, Via Reali di Bulgaria, Brindisi, Mesagne,
• Alessandro Distante, Euro Mediterranean Biomedical Institute (ISBEM) Research Centre, Via Reali di Bulgaria, Brindisi, Mesagne,
• Gian Luca Di Tanna, La Sapienza University of Rome, Piazzale Aldo Moro 5, Rome, 00185, Italy
• Maria Luisa Brandi, University of Florence, Viale Pieraccini 18, Florence
• Alfredo Mazza, College of Science and Technology Temple University
• Ignazio R Marino, Thomas Jefferson UniversityFollow
• Antonio Giordano, University of Siena, Strada delle Scotte, Siena, 53100, Italy

Document Type

Article

Publication Date

1-1-2012

Comments

This article has been peer reviewed. It was published in: Journal of experimental & clinical cancer research : CR

2012 Nov 20;31:96

The published version is available at DOI: 10.1186/1756-9966-31-96. Copyright © BioMed Central

Abstract

BACKGROUND: Where population coverage is limited, the exclusive use of Cancer Registries might limit ascertainment of incident cancer cases. We explored the potentials of Nationwide hospital discharge records (NHDRs) to capture incident breast cancer cases in Italy.

METHODS: We analyzed NHDRs for mastectomies and quadrantectomies performed between 2001 and 2008. The average annual percentage change (AAPC) and related 95% Confidence Interval (CI) in the actual number of mastectomies and quadrantectomies performed during the study period were computed for the full sample and for subgroups defined by age, surgical procedure, macro-area and singular Region. Re-admissions of the same patients were separately presented.

RESULTS: The overall number of mastectomies decreased, with an AAPC of -2.1% (-2.3 -1.8). This result was largely driven by the values observed for women in the 45 to 64 and 65 to 74 age subgroups (-3.0%, -3.4 -3.6 and -3.3%, -3.8 -2.8, respectively). We observed no significant reduction in mastectomies for women in the remaining age groups. Quadrantectomies showed an overall +4.7 AAPC (95%CI:4.5-4.9), with no substantial differences by age. Analyses by geographical area showed a remarkable decrease in mastectomies, with inter-regional discrepancies possibly depending upon variability in mammography screening coverage and adherence. Quadrantectomies significantly increased, with Southern Regions presenting the highest average rates. Data on repeat admissions within a year revealed a total number of 46,610 major breast surgeries between 2001 and 2008, with an overall +3.2% AAPC (95%CI:2.8-3.6).

CONCLUSIONS: In Italy, NHDRs might represent a valuable supplemental data source to integrate Cancer Registries in cancer surveillance.

Recommended Citation

Piscitelli, Prisco; Barba, Maddalena; Crespi, Massimo; Di Maio, Massimo; Santoriello, Antonio; D'Aiuto, Massiliamo; Fucito, Alfredo; Losco, Arturo; Pentimalli, Francesca; Maranta, Pasquale; Chitano, Giovanna; Argentiero, Alberto; Neglia, Cosimo; Distante, Alessandro; Di Tanna, Gian Luca; Brandi, Maria Luisa; Mazza, Alfredo; Marino, Ignazio R; and Giordano, Antonio, "The burden of breast cancer in Italy: mastectomies and quadrantectomies performed between 2001 and 2008 based on nationwide hospital discharge records." (2012). Department of Surgery Faculty Papers. Paper 87.
https://jdc.jefferson.edu/surgeryfp/87

PubMed ID

23168067