Document Type
Article
Publication Date
3-1-2026
Abstract
Objectives: A higher frequency of valvular heart disease is seen among Systemic Sclerosis (SSc) patients. Advanced aortic valve stenosis leads to significant morbidity in these patients with multiple other comorbidities. In this study, we aim to define the short- and long-term outcomes of transcatheter aortic valve replacement (TAVR) procedures in SSc patients. Methods: We undertook a retrospective chart review of all patients with SSc who underwent a TAVR procedure at our institution over a defined 11-year period. Demographics as well as short- and long-term outcomes were identified. Results: Fourteen SSc patients underwent a TAVR procedure between 2012 and 2023. They were predominantly older Caucasian female patients with limited cutaneous SSc (lcSSc) with advanced aortic stenosis. Only one patient had a re-admission within 30 days due to post-op heart failure and subsequently had to have the TAVR reversed to a SAVR. Conclusions: TAVR is a well-tolerated procedure in SSc patients with advanced aortic stenosis and multiple comorbidities.
Recommended Citation
Derk, Chris T.; Badali, Ahmadreza; Mehmetoglu, Esra; Mummadisetty, Anvitha; Syal, Amit; and Parperis, Konstantinos, "Transcatheter Aortic Valve Replacement in Systemic Sclerosis: A Case Series and Review of Short- and Long-Term Outcomes" (2026). Student Papers, Posters & Projects. Paper 195.
https://jdc.jefferson.edu/student_papers/195
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Language
English
Comments
This article is the author’s final published version in Mediterranean Journal of Rheumatology, Volume 37, Issue 1, 2026, Pages 236-242.
The published version is available at https://doi.org/10.31138/mjr.280525.ehr. Copyright © 2026 The Author(s).