Document Type
Article
Publication Date
7-22-2024
Abstract
Chronic myelomonocytic leukemia (CMML) is an uncommon myeloid neoplasm with myeloproliferative and myelodysplastic features characterized by peripheral monocytosis and cytopenia. CMML may have cutaneous manifestations known as leukemia cutis (LC). LC in the setting of CMML may portend malignant transformation to acute myeloid leukemia (AML). The distribution and morphologic features of LC in CMML are highly variable and often nonspecific. CMML may coexist with numerous secondary autoimmune and inflammatory processes; this phenomenon presents a clinical challenge which can delay correct diagnosis and appropriate therapeutic management. Thus, careful consideration of extramedullary manifestations of CMML and associated autoimmune conditions in the skin and other organs greatly aids in the correct and timely diagnosis.
Recommended Citation
Harper, Kamran K.; Mutch, Vanessa; Safran, Jordan Philip; Wu, Daisy; Aggarwal, Nidhi; Maheshwari, Ekta; Weinstock, Allison K.; Gibson, Kevin F.; Errera, Marie-Helene; Hou, Jing-Zhou; Karunamurthy, Arivarasan D.; and Bunimovich, Yuri L., "Leukemia Cutis and Anterior Uveitis Associated With Chronic Myelomonocytic Leukemia" (2024). Student Papers, Posters & Projects. Paper 145.
https://jdc.jefferson.edu/student_papers/145
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Language
English
Comments
This article is the author's final published version in JAAD Case Reports, Volume 52, October 2024, Pg. 21-24.
The published version is available at https://doi.org/10.1016/j.jdcr.2024.07.001. Copyright © 2024 by the American Academy of Dermatology, Inc. Published by Elsevier Inc.