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Course: LS 803 Contemporary Topics Research

Course Instructor: Dr. Paula McCourt

Department: Medical Laboratory Sciences and Biotechnology Department, Jefferson College of Health Professionals


Regenerative Medicine, powered by stem cells, is an emerging field with continuous advancements that impact lives. Stem cells are the precursor to all human cells, and unique characteristics such as the ability to self-renewal and differentiate into other cell types make them versatile in research. Embryonic stem cells (ESCs) have a greater differentiation potential and can increase into almost any cell type, such as bone, skin, or brain. On the contrary, adult stem cells are more restricted in the cell type they will become. In research, various factors can be combined with stem cells, and these cells are genetically alternated for a designated purpose, called Induced Pluripotent Cells (iPSCs). TERM is the field that combines Tissue Engineering and Regenerative Medicine to facilitate tissue regeneration and replace damaged tissue or organs. Prior research and development have led to the creation of multiple prototypes of organs, including the ear, trachea, and skin. These offer viable alternatives to traditional transplant procedures, and with the aging population, the demand is higher. Current therapeutic approaches using stem cell-based treatments include bone marrow transplants for blood disorders, skin grafts for burn patients, and even use in neurodegenerative diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis. Stem cells have become an indispensable component of Regenerative Medicine, driving continued advancements and innovations in this field. This review paper will discuss the importance and practical implications of stem cell research concerning tissue regeneration and the Biomedical field. This paper will include details of current therapeutic approaches while highlighting how indispensable stem cells have become in Regenerative Medicine.