Document Type
Article
Publication Date
8-22-2024
Abstract
BACKGROUND: Cutaneous squamous cell carcinoma (cSCC) is the most common keratinocyte carcinoma in dark-skinned ethnic groups. Available studies are primarily focused on white populations, with fewer data available for black Africans, including Ethiopians. Therefore, less priority may be given to treatment and prevention in this population.
OBJECTIVE: To determine the prevalence and risk factors of cSCC among patients presenting to All Africa Leprosy, Tuberculosis, and Rehabilitation Training Center , Addis Ababa, Ethiopia.
METHODS: A literature review was performed to determine existing knowledge. A retrospective descriptive cross-sectional study was then conducted based on stored data of confirmed cases of cSCC from 2011 to 2021 at ALERT. Demographics, other parameters related to cSCC (size, anatomic location, degree of differentiation, metastasis, and recurrence), and potential risk factors including scars, burns, HIV status, xeroderma pigmentosum, and leprosy were collected and entered on a prepared data extraction sheet and analyzed using SPSS version 25 manufactured by IBM.
RESULTS: Among 15,075 total pathologic samples reviewed, 3.8% (
CONCLUSION: The biologic significance of ulceration in this population is unclear. Ulceration may indicate chronic wounds or Marjolin's ulcers. High rates of metastasis call for a better understanding of risk factors, preventive measures, and early diagnosis. This model of research may serve as a foundation for future nationwide investigations through the Federal Ministry of Health of Ethiopia's Disease Prevention and Control Directorate.
Recommended Citation
Yosef, Tizita; Ergete, Wondwossen; Revankar, Rishab R; Patel, Heli A.; Kumsa, Tsegaye Hailu; Patel, Vishal A; Girma, Selfu; and Stoff, Benjamin K, "Epidemiologic Trends in Cutaneous Squamous Cell Carcinoma from 2011 to 2021 at All Africa Leprosy, Tuberculosis, and Rehabilitation Training Center (ALERT) in Addis Ababa, Ethiopia" (2024). SKMC Student Presentations and Publications. Paper 21.
https://jdc.jefferson.edu/skmcstudentworks/21
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Language
English
Comments
This article is the author's final published version in JAAD International, Volume 17, December 2024, pages 99-103.
The published version is available at https://doi.org/10.1016/j.jdin.2024.07.014.
Copyright © 2024 Published by Elsevier Inc. on behalf of the American Academy of Dermatology, Inc.