Document Type
Article
Publication Date
7-24-2026
Abstract
CONTEXT: Psychiatric comorbidity has been associated with worse perioperative outcomes and greater healthcare utilization after spine surgery.
AIMS: This study compared complications and healthcare utilization among posterior cervical decompression and fusion (PCDF) patients with depression, psychotic disorders, or no mental-health diagnosis.
SETTINGS AND DESIGN: Retrospective cohort analysis of the National Inpatient Sample from 2016 to 2022.
MATERIALS AND METHODS: The database was queried for elective adult PCDF encounters. Mental-health exposures were defined using Elixhauser indicators for depression and psychoses. Outcomes included medical complications, non-routine discharge, inpatient mortality, length of stay (LOS), and costs.
STATISTICAL ANALYSIS USED: Chi-square and multivariate logistic regression analyses were performed. Significance was set at the
RESULTS: We identified 167,480 weighted admissions: 129,205 with no mental-health diagnosis, 32,500 with depression, and 5,775 with psychotic disorders. Depression was associated with higher odds of cardiovascular complications (odds ratio [OR]: 1.20,
CONCLUSIONS: Depression and psychotic disorders are common in PCDF and are linked to worse outcomes and higher resource use.
Recommended Citation
Mastrokostas, Leonidas E.; Mastrokostas, Paul G.; Yusupov, Daniel; Razi, Abigail; Lavi, Aaron B.; Schwartz, Luke B.; Inzerillo, Sean; Said, Mohamed; Kucherina, Alexander; Jagtiani, Pemla; Monas, Arie; Houten, John K.; Kepler, Christopher K; Monsef, Jad Bou Bou; Razi, Afshin E.; and Ng, Mitchell K., "Depression and Psychotic Disorders Elevate Inpatient Burden After Posterior Cervical Decompression and Fusion: Prioritizing Screening and Targeted Discharge Planning" (2026). Rothman Institute Papers. Paper 337.
https://jdc.jefferson.edu/rothman_institute/337
Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Language
English

Comments
This article is the author's final published version in Journal of Craniovertebral Junction and Spine, Volume 17, Issue 4, July 2026, Pages 434-440.
The published version is available at https://doi.org/10.4103/jcvjs.jcvjs_95_26. Copyright © 2026 Journal of Craniovertebral Junction and Spine.