Document Type
Article
Publication Date
8-1-2023
Abstract
With a significant rise in the number of arthroplasty procedures performed worldwide, the increasing revision burden posed by periprosthetic joint infection (PJI) is a matter of growing concern. In spite of various attempts to diagnose PJI, there are no defined tests that can be called a gold standard. Given the importance of early diagnosis in PJI, newer tests and biomarkers have been introduced to improve cumulative diagnostic accuracy. Novel biomarkers like calprotectin, lipocalcin, monocyte-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and platelet-to-mean platelet volume ratio have demonstrated a potential as diagnostic biomarkers for PJI. This article discusses the relevance of available and newly described diagnostic biomarkers to provide a perspective on the practical applicability in current medical practice, as well as highlights some recent advances in biomarkers for the diagnosis of PJI.
Recommended Citation
Tripathi, Saksham; Tarabichi, Saad; Parvizi, Javad; and Rajgopal, Ashok, "Current relevance of biomarkers in diagnosis of periprosthetic joint infection: an update." (2023). Rothman Institute Faculty Papers. Paper 228.
https://jdc.jefferson.edu/rothman_institute/228
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Language
English
Comments
This article is the author's final published version in Arthroplasty, Volume 5, Issue 1, 2023, Article number 41.
The published version is available at https://doi.org/10.1186/s42836-023-00192-5.
Copyright © The Author(s) 2023
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