Epstein-Barr virus-associated hemophagocytic syndrome mimicking severe sepsis.

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This article has been peer reviewed. It was published in: Journal of Emergencies, Trauma, and Shock

Volume 1, Issue 2, Jul-Dec. 2008, Pages 119-122.

The published version is available at DOI: 10.4103/0974-2700.43198. Copyright © Journal of Emergencies, Trauma, and Shock


Severe sepsis is amongst the most common reasons for admission to the intensive care unit (ICU) throughout the world and is a common cause of death. The diagnosis of sepsis is usually straightforward, being based on a constellation of clinical and laboratory features. Noninfectious disorders, including pancreatitis, drug reactions, and autoimmune disorders, may cause a systemic inflammatory response that mimics sepsis. We present the case of a 32-year-old male with Epstein-Barr virus-associated hemophagocytic syndrome who presented to the ICU with features of severe sepsis which progressed to multisystem organ failure and death despite aggressive supportive measures.

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