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This article is the author's final published version in Trials, Volume 23, Issue 1, December 2022, Article number 927.

The published version is available at Copyright © The Author(s) 2022.


The coronavirus disease 2019 (COVID-19) pandemic resulted in severe interruptions to clinical research worldwide. This global public health crisis required investigators and researchers to rapidly develop and implement new strategies and solutions to mitigate its negative impact on the progress of clinical trials. In this paper, we describe the challenges, strategies, and lessons learned regarding the continuation of a supportive oncology clinical trial during the pandemic. We hope to provide insight into the implementation of clinical trials during a public health emergency to be better prepared for future instances.

Trial registration:, a service of the US National Institute of Health (NCT03030859). Registered on 22 January 2017.

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Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

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