Document Type


Publication Date

December 2006


This article has been peer reviewed. It was published in Psychiatric Clinics of North America 29(4): 841-853, December 2006. The published version is available at Copyright is retained by Elsevier, Inc.


Sleep is a vital, highly organized process regulated by complex systems of neuronal networks and neurotransmitters. Sleep plays an important role in the regulation of central nervous system and body physiologic functions. Sleep architecture changes with age and is easily susceptible to external and internal disruption. Reduction or disruption of sleep can affect numerous functions varying from thermoregulation to learning and memory during the waking state.