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This article has been peer reviewed. It is the authors' final version prior to publication in Clinical and Translational Science Volume 4, Issue 1, February 2011, Pages 69-71. The published version is available at DOI: 10.1111/j.1752-8062.2011.00261.x. Copyright © John Wiley Sons, Inc.


Vaccines, analgesia, and antibiotics embody some of the most

enduring therapeutic breakthroughs that have transformed

medicine. Building on such fine paradigms of biomedical

innovation, the evolution of technologies has increasingly

sparked spectacular advances across the continuum of wellness

and disease-spanning medical and surgical specialties. Discovery

science—fueled by government and private sector resources—has

systematically instituted the principles of modern healthcare

delivery ensuring that medical practice is based on up-to-date

scientifi c evidence. Th e harmony between science, technology,

and resources has culminated in a golden age of discovery and

translation, eradicating infections, curing cancers, and palliating

endocrine and metabolic diseases. Indeed, proven therapeutic and

preventive approaches have progressively moved into everyday




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