Beta-adrenergic agents have been used in pregnant women for the treatment of premature labor and for the treatment of asthma. Concerns have been expressed that exposure to terbutaline, a beta-2 adrenergic agonist, may increase the risk of autism spectrum disorders (ASDs) in the offspring. This hypothesis deserves critical review, given the number of patients exposed to the drug in the last two decades. The results are important to both the obstetricians and patients who weigh the risks and benefits of interventions and to the pediatricians who counsel the families of affected children.
Rodier, Patricia; Miller, Richard K; and Brent, Robert L, "Does treatment of premature labor with terbutaline increase the risk of autism spectrum disorders?" (2011). Department of Pediatrics Faculty Papers. Paper 36.