Document Type
Article
Publication Date
5-25-2026
Abstract
BACKGROUND: Severe right ventricular (RV) dilatation and exercise intolerance are considered indications for pulmonary valve replacement in surgically repaired tetralogy of Fallot (rTOF).
METHODS AND RESULTS: Cardiopulmonary exercise testing (CPET) and cardiac magnetic resonance (CMR) were performed in rTOF patients with pulmonary insufficiency (PI). Oxygen pulse (OP), calculated as oxygen consumption (V̇O
CONCLUSIONS: A smaller RV was associated with worse exercise performance, indicating exercise intolerance is independent of RV dilatation in young rTOF with PI and represents a unique pathological entity responsible for reduced exercise performance.
Recommended Citation
Mhanna, Christiane; Kourpas, Katerina; and Tsuda, Takeshi, "Smaller Right Ventricle Results in Poorer Exercise Performance in Young Patients With Repaired Tetralogy of Fallot" (2026). Department of Pediatrics Faculty Papers. Paper 202.
https://jdc.jefferson.edu/pedsfp/202
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
PubMed ID
41638666
Language
English
Comments
This article is the author's final published version in Circulation journal : official journal of the Japanese Circulation Society, Volume 90, Issue 6, May 2026, Pages 651-660.
The published version is available at https://doi.org/10.1253/circj.CJ-25-0846. Copyright © Japanese Circulation Society.