Reducing Symptomatic Postoperative Hyponatremia after Endoscopic Pituitary Tumor Surgery

Start Date

5-15-2025 9:30 AM

End Date

5-15-2025 11:30 AM

Description

Background

Problem Statement: Postoperative moderate to severe hyponatremia is the most cause of readmission following transsphenoidal endoscopic resection of pituitary tumors, with reported rates up to 8%. The pathophysiology of water balance after pituitary tumor surgery is as below:

[See figure]

Although postoperative diabetes insipidus (resulting in hypernatremia) is a concern in the immediate postoperative period, this is often transient, and thus it has been proposed to implement a postoperative fluid restriction to prevent delayed hyponatremia

Keywords

hyponatremia, pituitary tumor

Comments

Presented at the 2025 Jefferson Health Equity and Quality Improvement (HEQI) Summit.

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May 15th, 9:30 AM May 15th, 11:30 AM

Reducing Symptomatic Postoperative Hyponatremia after Endoscopic Pituitary Tumor Surgery

Background

Problem Statement: Postoperative moderate to severe hyponatremia is the most cause of readmission following transsphenoidal endoscopic resection of pituitary tumors, with reported rates up to 8%. The pathophysiology of water balance after pituitary tumor surgery is as below:

[See figure]

Although postoperative diabetes insipidus (resulting in hypernatremia) is a concern in the immediate postoperative period, this is often transient, and thus it has been proposed to implement a postoperative fluid restriction to prevent delayed hyponatremia