Reducing Symptomatic Postoperative Hyponatremia after Endoscopic Pituitary Tumor Surgery
Start Date
5-15-2025 9:30 AM
End Date
5-15-2025 11:30 AM
Description
Background
Problem Statement: Postoperative moderate to severe hyponatremia is the most cause of readmission following transsphenoidal endoscopic resection of pituitary tumors, with reported rates up to 8%. The pathophysiology of water balance after pituitary tumor surgery is as below:
[See figure]
Although postoperative diabetes insipidus (resulting in hypernatremia) is a concern in the immediate postoperative period, this is often transient, and thus it has been proposed to implement a postoperative fluid restriction to prevent delayed hyponatremia
Keywords
hyponatremia, pituitary tumor
Reducing Symptomatic Postoperative Hyponatremia after Endoscopic Pituitary Tumor Surgery
Background
Problem Statement: Postoperative moderate to severe hyponatremia is the most cause of readmission following transsphenoidal endoscopic resection of pituitary tumors, with reported rates up to 8%. The pathophysiology of water balance after pituitary tumor surgery is as below:
[See figure]
Although postoperative diabetes insipidus (resulting in hypernatremia) is a concern in the immediate postoperative period, this is often transient, and thus it has been proposed to implement a postoperative fluid restriction to prevent delayed hyponatremia


Comments
Presented at the 2025 Jefferson Health Equity and Quality Improvement (HEQI) Summit.