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ACT is commonly used for heparin anticoagulation monitoring during procedures including cardiopulmonary bypass surgery, coronary angioplasty, and interventional radiology. To prevent thrombosis, moderate to high levels of heparin anticoagulation are required. The Hemochron Signature Elite (HSE, Accriva Diagnostics, formerly ITC, San Diego, CA) was implemented at TJUH as a replacement for the older model Hemochron Response (Accriva/ITC Model HRS.110, San Diego, CA). Operating room (OR) perfusionists reported irreproducible high results using HSE that could not be explained clinically. In consideration of use of i-STAT analyzers (Abbott Point of Care, Princeton, NJ) as an alternative to HSE, we performed a comparison of ACT results as analyzed by HSE and i-STAT (Abbott Point of Care, Princeton, NJ) analyzers.
Poster presented at: American Association for Clinical Chemistry Annual Scientific Meeting in Philadelphia PA.
Activated Clotting Time (ACT): Comparison of the Hemochron Signature Elite and the Abbott i-STAT
Medical Anatomy | Medical Cell Biology | Medical Pathology
Evans, Lilah; Gallo, Susanne; Leo, Joseph J.; and Goldsmith, PhD, FACB, Barbara, "Activated Clotting Time (ACT): Comparison of the Hemochron Signature Elite and the Abbott i-STAT" (2016). Department of Pathology, Anatomy, and Cell Biology Posters. 5.