Document Type
Article
Publication Date
10-10-2023
Abstract
Aberrant migration of parathyroid glands from their embryologic origin may result in undescended parathyroid glands. We present a case of an ectopic parathyroid adenoma at the level of the pyriform sinus. A 41-year-old female was evaluated for primary hyperparathyroidism. Following non-localizing ultrasound and planar sestamibi imaging, the patient underwent SPECT/CT and 4-D computed tomography demonstrating evidence of an ectopic parathyroid adenoma. The surgical approach was modified based on the location. Following extirpation, PTH fell from 80 to 16 pg/mL, and the 15-min post-excision level remained stable at 14pg/mL, indicating a biochemical cure. While rare, undescended parathyroid adenoma should be considered when preoperative imaging fails to identify a target adenoma or after unsuccessful surgery. The combined use of 99m Tc-MBI or 4D CT and other anatomical scans may improve diagnostic accuracy. Due to the potential need to perform a second incision to conduct a four-gland exploration, preoperative patient discussion regarding surgical risks may differ from that of a standard parathyroidectomy.
Recommended Citation
Sina, Elliott M.; Han, Chihun J.; and Cottrill, Elizabeth E., "Undescended Superior Parathyroid: A Case Report" (2023). Department of Otolaryngology - Head and Neck Surgery Faculty Papers. Paper 88.
https://jdc.jefferson.edu/otofp/88
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
PubMed ID
37830070
Language
English
Comments
This article is the author’s final published version in Clinical Case Reports, Volume 11, Issue 10, October 2023, Article number e7987.
The published version is available at https://doi.org/10.1002%2Fccr3.7987. Copyright © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
Publication made possible in part by support through a transformative agreement between Thomas Jefferson University and the publisher.