Basic science research into the mechanism of the development of endometriosis, its persistence and resulting pain has begun to improve our understanding of how various therapeutic options work. While none of the available treatments resolves the underlying disease process, there are a growing number of alternatives. One of the more recent classes of medical options includes the GnRH agonist and antagonists. While at present this class of medical options is the most expensive and involved in implementation, they prove invaluable in terms of offering an aggressive, successful alternative for many patients. Furthermore, they may act directly on endometrial lesions in a therapeutic manner. This discussion will be oriented toward endometriosis pain management, but many of the medical manipulations may be therapeutic for infertility treatment as well if only by preventing the need for aggressive or emergency surgical management of endometriosis, especially in young women.
Batzer, Frances R., "GnRH agonist and antagonist: Options for endometriosis pain treatment " (2006). Department of Obstetrics and Gynecology Faculty Papers. Paper 3.