Update on Intra-Arterial Chemotherapy for Retinoblastoma.

Authors

Mario Zanaty, Department of Neurological Surgery, Thomas Jefferson UniversityFollow
Guilherme Barros, Department of Neurosurgery, Thomas Jefferson University
Nohra Chalouhi, MD, Department of Neurosurgery, Thomas Jefferson UniversityFollow
Robert M Starke, Department of Neurosurgery, University of VirginiaFollow
Philip Manasseh, Department of Neurosurgery, Thomas Jefferson UniversityFollow
Stavropoula I. Tjoumakaris, Department of Neurosurgery, Thomas Jefferson UniversityFollow
Carol L Shields, Thomas Jefferson UniversityFollow
David Hasan, Department of Neurosurgery, University of Iowa School of MedicineFollow
Ketan Bulsara, Department of Neurosurgery, Yale University School of Medicine
Robert H. Rosenwasswer MD, Department of Neurosurgery, Thomas Jefferson UniversityFollow
Pascal Jabbour MD, Thomas Jefferson UniversityFollow

Document Type

Article

Publication Date

2014

Comments

This article has been peer reviewed. It is the author’s final published version in Scientific World Journal Volume 2014, Article number 869604.

The published version is available at DOI: 10.1155/2014/869604. Copyright © Hindawi Publishing Corporation

Abstract

The tools for managing retinoblastoma have been increasing in the past decade. While globe-salvage still relies heavily on intravenous chemotherapy, tumors in advanced stage that failed chemotherapy are now referred for intra-arterial chemotherapy (IAC) to avoid enucleation. However, IAC still has many obstacles to overcome. We present an update on the indications, complications, limitations, success, and technical aspects of IAC. Given its safety and high efficacy, it is expected that IAC will replace conventional strategies and will become a first-line option even for tumors that are amenable for other strategies.

Recommended Citation

Zanaty, Mario; Barros, Guilherme; Chalouhi, MD, Nohra; Starke, Robert M; Manasseh, Philip; Tjoumakaris, Stavropoula I.; Shields, Carol L; Hasan, David; Bulsara, Ketan; Rosenwasswer MD, Robert H.; and Jabbour, Pascal MD, "Update on Intra-Arterial Chemotherapy for Retinoblastoma." (2014). Department of Neurosurgery Faculty Papers. Paper 69.
https://jdc.jefferson.edu/neurosurgeryfp/69

PubMed ID

25405236