Document Type
Article
Publication Date
8-27-2023
Abstract
Opportunistic fungal infections are a major cause of mortality in immunosuppressed patients, with mucormycosis and aspergillosis as two of the most commonly identified fungal organisms. Coinfection with mucormycosis and aspergillosis is rare, but cases have been reported in literature, most commonly presenting as disseminated invasive fungal infection with cerebrorhino-orbital involvement in an immunocompromised patient. Infections are most commonly caused by direct implantation of spores with localised angioinvasion. Haematogenous spread is rare, with most cases secondary to haematological malignancies or intravenous drug use. Coinfection with mucormycosis and aspergillosis portends a poor prognosis, with a high mortality rate. Thus, prompt recognition and intervention are crucial to prevent poor outcomes. In this unique case report, we describe a case of isolated cerebral mucormycosis and aspergillosis coinfection, not previously reported in literature.
Recommended Citation
Sun, George; Weiss, Allison; Zhao, Joy; Silver, Mitchell; DeMaio, Michael; and Dehbashi, Sara, "Isolated Cerebral Mucormycosis and Aspergillosis Coinfection in an Immunocompromised Adult" (2023). Department of Neurology Faculty Papers. Paper 328.
https://jdc.jefferson.edu/neurologyfp/328
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License
PubMed ID
37640409
Language
English
Comments
This article is the author's final published version in BMJ Case Reports, Volume 16, 2023, Article number e255909.
The published version is available at https://doi.org/10.1136/bcr-2023-255909. Copyright © BMJ Publishing Group Limited 2023.