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Racial and ethnically diverse populations are underrepresented in clinical research trials. This lack of inclusion contributes to marked disparities in healthcare. Engaging disadvantaged communities has shown to be effective in ensuring that people from diverse backgrounds participate in clinical research. Community Based Participatory Research (CBPR) is an approach that involves community members as equal partners in the research process. Despite the growing awareness of its benefits, there are inconsistencies in CBPR implementation literature, and there is no universal CBPR evaluation tool. The purpose of this rapid review of the literature is to assess the potential for CBPR to enhance recruitment and retention rates of marginalized populations in clinical research trials. Additionally, this review aims to evaluate the rigor of the CBPR approaches in eight clinical studies. A rapid review of the literature was performed utilizing two research databases, PubMed and CINAHL. Peer-reviewed articles were screened and either included or excluded based on specific criteria. Eight articles were selected and reviewed. Data were extracted on each study population’s characteristics, recruitment and retention rates, and community member involvement in the research process. Across a range of clinical study designs and areas of focus, most articles demonstrated high rates of recruitment and retention. However, community member participation was variable across the research process for each article. CBPR holds promise for diversifying clinical research study populations, thereby increasing the generalizability of clinical interventions. Implementing CBPR allows researchers to understand the barriers communities face in achieving health equity. Recommendations for future research initiatives are discussed.