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Presentation: 5:10

Poster attached as supplemental file below


Despite substantial progress, the world failed to achieve reductions in under-5 mortality consistent with the Millennium Development Goals, with nearly 5 million children dying each year. Nearly 99% of these deaths occur in developing countries, and 40% of these deaths occur within the first month of life. With many low-income countries facing high burdens of infectious diseases, maternal immunization (MI) presents a pathway to provide newborns immunological protection from communicable illnesses with lethal consequences. This rapid systematic review aimed to identify the effects of various personal and interpersonal influences affecting pregnant women’s acceptance of MI in developing countries and analyzed seven articles that discussed relevant factors. The clearest result appearing in both quantitative and qualitative studies showed prohibitive effects exhibited by husbands on their wives’ uptake of maternal immunization. Basic levels of maternal knowledge surrounding MI and positive newborn outcomes were linked with favorable attitudes and intentions to accept MI during pregnancy. Income was associated with higher MI uptake only for upper-income strata, while maternal age, education level, parity, and personal social network showed no clear relationships. These findings show a critical need to expand antenatal care education that includes husbands to create positive involvements throughout a pregnancy. Increasing maternal knowledge surrounding MI in concert with spousal education could have a beneficial, synergistic effect on MI coverage. Because many developing areas lack plentiful resources and substantial health infrastructure, these interventions could serve as more efficient and cost-effective alternatives that could achieve immediate reductions in infant mortality across the globe.