De Novo Fibrillary Glomerulonephritis (FGN) in a Renal Transplant with Chronic Hepatitis C.

Authors

E J Filippone, Thomas Jefferson UniversityFollow
Christine Chmielewski, Thomas Jefferson UniversityFollow
Rakesh Gulati, Thomas Jefferson UniversityFollow
Eric Newman, Thomas Jefferson UniversityFollow
John Farber, Thomas Jefferson UniversityFollow

Document Type

Article

Publication Date

1-1-2013

Comments

This article has been peer reviewed. It was published in: Case reports in transplantation.

2013;2013:978481.

The published version is available at DOI: 10.1155/2013/978481. Copyright © Hindawi

Abstract

Chronic hepatitis C viremia (HepC) has been associated with numerous renal manifestations both in native kidneys and in the setting of renal transplantation. Glomerulonephritis (GN) of the renal allograft in the setting of HepC most commonly manifests as type 1 membranoproliferative GN (MPGN), either representing recurrence of the original disease or arising de novo. Other GNs were reported after transplantation in the patient with HepC including membranous nephropathy and thrombotic microangiopathy, as well as an enhanced susceptibility to transplant glomerulopathy. We describe the first case of de novo fibrillary GN in a renal transplant patient with HepC where the primary renal disease was biopsy proven type 1 MPGN. We discuss this relationship in detail.

Recommended Citation

Filippone, E J; Chmielewski, Christine; Gulati, Rakesh; Newman, Eric; and Farber, John, "De Novo Fibrillary Glomerulonephritis (FGN) in a Renal Transplant with Chronic Hepatitis C." (2013). Department of Medicine Faculty Papers. Paper 98.
https://jdc.jefferson.edu/medfp/98

PubMed ID

23844313