Cdo patterns the musculature of the esophagus and is required for esophageal motility in mice

Authors

Anthony I. Romera, Mount Sinai School of Medicine
Jagmohan Singhb, Thomas Jefferson University
Satish Rattan, Thomas Jefferson UniversityFollow
Robert S. Krauss, Thomas Jefferson University

Document Type

Presentation

Publication Date

5-21-2012

Comments

Poster presented at: Digestive Disease Week (DDW) International meeting in San Diego, California.

Abstract

Introduction:

Cdo is a multifunctional cell surface co-receptor that promotes Hedgehog signaling during rostroventral midline development and cadherin-mediated signaling during skeletal myogenesis. We report here novel roles for Cdo in patterning of the murine esophageal musculature and esophageal motility disorders such as achalasia.

Recommended Citation

Romera, Anthony I.; Singhb, Jagmohan; Rattan, Satish; and Krauss, Robert S., "Cdo patterns the musculature of the esophagus and is required for esophageal motility in mice" (2012). Department of Medicine Faculty Papers. Paper 78.
https://jdc.jefferson.edu/medfp/78