Document Type
Article
Publication Date
11-18-2024
Abstract
AIMS: Alcohol consumption along with negative sequelae from excess alcohol intake increased during the COVID-19 pandemic. We evaluated the association between binge alcohol use and long-term functional outcomes among COVID-19-positive individuals.
METHODS: Using a prospective, longitudinal, multisite cohort study design, we evaluated the association between binge alcohol use and mental and physical functional outcomes using Patient-Reported Outcomes Measurement Information System (PROMIS)-29 scores three and six months postinfection. Eligible patients were those who presented with COVID-19-like symptoms, tested positive for COVID-19, and completed a three-month survey. Binge drinking was identified at the time of infection using the Tobacco, Alcohol, Prescription medication and other Substance use screener. Generalized estimating equation models, adjusted for demographic characteristics, social determinants of health, substance use, comorbidities, and COVID-19 vaccine status, were used to assess the association between binge alcohol use and mental and physical functional outcomes.
RESULTS: Of 3529 individuals, 23.7% screened positive for binge drinking. At three months, prior self-reported binge drinking was associated with differences in physical function [estimate: 1.08; 95% confidence interval (CI) 0.44, 1.71], pain interference (estimate: -0.86; 95% CI -1.57, -0.15), and physical health (estimate: 1.09; 95% CI 0.43, 1.75). At six months, no associations were found between binge drinking and outcomes.
CONCLUSIONS: Binge alcohol use before COVID-19 infection was associated with statistically significant but clinically irrelevant improvements in function at three months, which were not sustained at six months. Postinfectious and postpandemic stressors may have played a larger impact on functional outcomes than binge alcohol use. A higher frequency of binge drinking and its association with functional outcomes, particularly among individuals with COVID-19 warrants further study.
Recommended Citation
Tong, Sebastian T.; Gottlieb, Michael; Ebna Mannan, Imtiaz; Zheng, Zihan; Sinha, Manisha; Santangelo, Michelle; Gatling, Kristyn; Kean, Efrat; Watts, Phillip; Wang, Ralph; Montoy, Juan Carlos; Idris, Ahamed; MacDonald, Samuel; Huebinger, Ryan; Hill, Mandy; O'Laughlin, Kelli N; Gentile, Nicole L.; Dorney, Jocelyn; Malicki, Caitlin; Elmore, Joann G.; Diaz Roldan, Kate; Chan, Gary; Lin, Zhenqiu; Weinstein, Robert A.; and Stephens, Kari A., "Association of Binge Alcohol Use With Functional Outcomes Among Individuals With COVID-19 Infection" (2024). Department of Medicine Faculty Papers. Paper 533.
https://jdc.jefferson.edu/medfp/533
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
PubMed ID
39745829
Language
English
Comments
This article is the author's final published version in Alcohol and Alcoholism, Volume 60, Issue 1, November 2024, Article Number agae086.
The published version is available at https://doi.org/10.1093/alcalc/agae086. Copyright © The Author(s).