Disseminated Nocardia cyriacigeorgia causing pancreatitis in a haploidentical stem cell transplant recipient.

Authors

Jason Chen, MD, Department of Medical Oncology, Sidney Kimmel Medical College of Thomas Jefferson UniversityFollow
Jonathan Pan, MD, Department of Medical Oncology, Sidney Kimmel Medical College of Thomas Jefferson UniversityFollow
Joanne Filicko-O'Hara, Department of Medical Oncology, Sidney Kimmel Medical College of Thomas Jefferson UniversityFollow
Margaret Kasner, Department of Medical Oncology, Sidney Kimmel Medical College of Thomas Jefferson UniversityFollow
Phyllis Flomenberg, Division of Infectious Diseases, Department of Medicine, Sidney Kimmel Medical College of Thomas Jefferson UniversityFollow

Document Type

Article

Publication Date

6-27-2017

Comments

This article has been peer reviewed. It was published in: IDCase.

Volume 9, 2017, Pages 73-76.

The published version is available at DOI:10.1016/j.idcr.2017.05.005

Copyright © 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Abstract

We report the first published case of acute pancreatitis secondary to disseminated nocardiosis in a hematopoietic stem cell transplant (HSCT) recipient on chronic immunosuppression for graft-versus-host disease (GVHD). Nocardiosis in the HSCT population is relatively rare, and has not yet been described in haploidentical HSCT recipients. Our patient is a 28-year-old male with a history of haploidentical HSCT and GVHD of the skin and lung who was admitted to the hospital with acute pancreatitis. The workup for the etiology of his pancreatitis was initially unrevealing. He subsequently developed worsening sepsis and respiratory failure despite broad spectrum antimicrobials. After multiple bronchoscopies and pancreatic fluid sampling, he was found to have disseminated nocardiosis with Nocardia cyriacigeorgia.

Recommended Citation

Chen, MD, Jason; Pan, MD, Jonathan; Filicko-O'Hara, Joanne; Kasner, Margaret; and Flomenberg, Phyllis, "Disseminated Nocardia cyriacigeorgia causing pancreatitis in a haploidentical stem cell transplant recipient." (2017). Department of Medicine Faculty Papers. Paper 210.
https://jdc.jefferson.edu/medfp/210

Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

PubMed ID

28706856