Prediction of Advanced Fibrosis in Nonalcoholic Fatty Liver Disease: An Enhanced Model of BARD Score.

Authors

Tae Hoon Lee, Department of Internal Medicine, Marshall University School of Medicine
Seung Hye Han, Critical Care Medicine, National Institute of Health
Ju Dong Yang, Division of Gastroenterology and Hepatology, Mayo Clinic
Donghee Kim, Division of Gastroenterology and Hepatology, Mayo Clinic; Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System
Monjur Ahmed, Division of Gastroenterology and Hepatology, Jefferson Medical College, Thomas Jefferson UniversityFollow

Document Type

Article

Publication Date

5-1-2013

Comments

This article has been peer reviewed. It was published in: Gut and Liver.

Volume 7, Issue 3, May 2013, Pages 323-328.

The published version is available at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661965/?report=classic DOI: 10.5009/gnl.2013.7.3.323

Copyright © 2007 by Gut and Liver.

Abstract

UNLABELLED: BACKGROUNDAIMS: The BARD score is a model to detect advanced liver fibrosis in nonalcoholic fatty liver disease (NAFLD) patients. The aims of this study were to identify additional factors and then to build an enhanced version of the BARD score.

METHODS: One hundred seven patients with biopsy-proven NAFLD were enrolled retrospectively. Logistic regressions were performed to identify independent risk factors for advanced liver fibrosis (stage 3 or 4). An enhanced model of the BARD score (BARDI score) was built and evaluated with a receiver operating characteristic (ROC) curve.

RESULTS: In multivariate analysis, age (odds ratio [OR], 0.89; p=0.04), aspartate aminotransferase/alanine aminotransferase ratio (OR, 1.73; p

CONCLUSIONS: The BARDI score had an improved PPV over the BARD score and maintained an excellent NPV. Further study is warranted for its external validation and comparison with other models.

Recommended Citation

Lee, Tae Hoon; Han, Seung Hye; Yang, Ju Dong; Kim, Donghee; and Ahmed, Monjur, "Prediction of Advanced Fibrosis in Nonalcoholic Fatty Liver Disease: An Enhanced Model of BARD Score." (2013). Department of Medicine Faculty Papers. Paper 101.
https://jdc.jefferson.edu/medfp/101

PubMed ID

23710314