Epigenetic Approaches to Epithelial Ovarian Cancer
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Therapeutic targeting ARID1A mutation in ovarian cancer (Clear Cell and Endometrioid).
- Synthetic lethality with ARID1A mutation
- Targeting mutual exclusivity between ARID1A and TP53 mutations
Overcoming platinum resistance using BET inhibitors (High-grade Serous).
Zhang, Rugang, "Epigenetic Approaches to Epithelial Ovarian Cancer" (2017). Kimmel Cancer Center Papers, Presentations, and Grand Rounds. Paper 48.