Severe Generalized Edema Associated with Phenelzine

Authors

William Bobo M.D., National Capital Cosortium Military Psychiatry Residency - National Naval Medical Center, Walter Reed Army Medical Center
Cheryl A. Hemme M.D., Department of Psych/Neurology, University of Missouri, Columbia School of Medicine

Abstract

Rabkin, et al. describes a 4% incidence of phenelzine-induced edema, which appears to be due to increased capillary permeability (1,2). This adverse effect is not further characterized in the literature and is not readily mentioned as one of the many drug effects that could result in severe physical morbidity. We present the case of a depressed patient who developed a generalized edema severe enough to deserve an extensive medical workup. Once the drug was tapered, the edema and its associated symptoms rapidly resolved.

Recommended Citation

Bobo, William M.D. and Hemme, Cheryl A. M.D. (2001) "Severe Generalized Edema Associated with Phenelzine," Jefferson Journal of Psychiatry: Vol. 16: Iss. 1, Article 7.
DOI: https://doi.org/10.29046/JJP.016.1.006
Available at: https://jdc.jefferson.edu/jeffjpsychiatry/vol16/iss1/7