•  
  •  
 
Jefferson Journal of Psychiatry

Abstract

This is a case report of late onset Tay-Sachs Disease diagnosed in a 14-year-old male non-Jewish adolescent who presented in a psychotic and catatonic state. The objective is to emphasize that Tay-Sachs disease can present with psychiatric symptoms, with a variety of phenotypes from infancy to adulthood, and can affect individuals other than Ashkenazi Jews. Amphiphilic drugs, including phenothiazine and tricyclic antidepressants, may worsen the course of the illness. Resistant catatonia can respond to an extended trial of high dose lorazepam.

Included in

Psychiatry Commons

Share

COinS