A 58-year-old woman with a history of morbid obesity, asthma, and prior warfarin use presented to the hospital with shortness of breath and a three-month history of painful, ulcerated ulcers with retiform purpura of her bilateral distal extremities. A punch biopsy specimen demonstrated focal necrosis and hyalinization of the adipose tissue with subtle arteriolar calcium deposition, findings consistent with calciphylaxis. We discuss the presentation of non-uremic calciphylaxis and review the risk factors, pathophysiology, and interdisciplinary management approach of this rare disease.
Nugent, Shannon; Karaisz, Fred; Elbadawi, Maisa; Touati, Andrew; Nikbakht, Neda; Lee, Jason B.; and Arif, Hasan, "An Unexpected Case of Non-uremic Calciphylaxis in a Patient With Multiple Risk Factors" (2022). Division of Internal Medicine Faculty Papers & Presentations. Paper 61.
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