Document Type
Article
Publication Date
4-20-2023
Abstract
Chronic hepatitis B remains a major public health concern and a leading cause of morbidity and mortality worldwide, specifically through its causative role in chronic liver disease and hepatocellular carcinoma. Worldwide, it affects up to 292 million people. In this paper, we review the historic discovery of the hepatitis B virus and chronicle the significant advances in our understanding of the virus and its interactions with the human host to cause disease. We also overview advancements in therapies for hepatitis B virus and the current absence of curative therapies and highlight on-going therapeutic efforts in search of curative therapies to control transmission and eradicate hepatitis B virus.
Recommended Citation
Bashir Hamidu, Rukaiya; Hann, Richard R.; and Hann, Hie-Won, "Chronicles of HBV and the Road to HBV Cure" (2023). Division of Gastroenterology and Hepatology Faculty Papers. Paper 91.
https://jdc.jefferson.edu/gastro_hepfp/91
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Language
English
Comments
This article is the author's final published version in Livers, Volume 3, Issue 2, 2023, Pg. 232 - 239.
The final published version is available at https://doi.org/10.3390/livers3020015. Copyright © 2023 by the authors. Licensee MDPI, Basel, Switzerland.