Document Type
Article
Publication Date
4-20-2026
Abstract
Gastrointestinal stricture can occur in the esophagus, stomach, small intestine, colon, and anorectum. Most of the strictures are benign. The prevalence of esophageal strictures (ES) secondary to eosinophilic esophagitis has increased. Pyloric stenosis (PS) is rarely seen in clinical practice. Sleeve stenosis (SS) and stomal stenosis or gastrojejunal anastomotic stricture (GJAS) are increasingly seen due to bariatric surgery. Crohn's disease (CD) remains a significant challenge even in the biologic era. The symptomatology of strictures depends on the location, severity, and underlying cause. Imaging studies and endoscopic procedures are the primary investigations to diagnose and evaluate strictures. Various treatment modalities are available to treat gastrointestinal strictures. Successful stricture treatment can significantly improve a patient's quality of life. Benign strictures carry a much better prognosis than malignant strictures. Multiple other factors influence response to treatment.
Recommended Citation
Ahmed, Monjur, "Stricturing Diseases of the Gastrointestinal Tract—Current Clinical Practice" (2026). Division of Gastroenterology and Hepatology Faculty Papers. Paper 128.
https://jdc.jefferson.edu/gastro_hepfp/128
Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
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Language
English

Comments
This article is the author's final published version in JGH Open, Volume10, Issue4, April 2026, Article number e70411.
The published version is available at https://doi.org/10.1002/jgh3.70411. Copyright © 2026 The Author(s).