Document Type
Article
Publication Date
12-1-2024
Abstract
BACKGROUND: Recent data showed an association between malnutrition and increased all-cause mortality and thromboembolic risk in patients with atrial fibrillation (AF). However, the impact of malnutrition on the clinical outcomes for patients undergoing catheter ablation for AF is still debated. Our study aimed to examine this relationship using all existing available data.
METHODS: We conducted a systematic review of MEDLINE and EMBASE databases from inception to April 2024, analyzing the association between malnutrition, assessed by the Geriatric Nutritional Risk Index (GNRI), and the risk of AF recurrence in patients who underwent catheter ablation for AF, compared to those without malnutrition. Relative Risk (RR) or hazard ratio (HR) and 95% CIs were retrieved from each study and combined using the generic inverse variance method.
RESULTS: We included 3 cohort studies with 1697 participants undergoing AF ablation (10.9%) who had malnutrition indicated by GNRI score below 98. Patients with malnutrition had a higher risk of AF recurrence following catheter ablation for AF compared to those without malnutrition (Pooled RR = 2.74, 95% CI 1.36-5.51,
CONCLUSIONS: Our pooled analysis indicates that malnourished patients undergoing catheter ablation for AF have an increased risk of AF recurrence compared to non-malnourished patients.
Recommended Citation
Wattanachayakul, Phuuwadith; Srikulmontri, Thitiphan; Prasitsumrit, Vitchapong; Suenghataiphorn, Thanathip; Danpanichkul, Pojsakorn; Kewcharoen, Jakrin; Charoenngam, Nipith; and Mainigi, Sumeet, "Malnutrition and Risks of Atrial Fibrillation Recurrence After Catheter Ablation" (2024). Einstein Health Papers. Paper 57.
https://jdc.jefferson.edu/einsteinfp/57
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Language
English
Comments
This article is the author’s final published version in the Journal of Arrhythmia, Volume 41, Issue 1, Feb 2025, Article number e13196.
The published version is available at https://doi.org/10.1002/joa3.13196. Copyright © 2024 The Author(s). Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of Japanese Heart Rhythm Society.
Publication made possible in part by support through a transformative agreement between Thomas Jefferson University and the publisher.