Document Type
Article
Publication Date
8-23-2022
Abstract
Background: Limited data is available on the comparison of outcomes of transradial (TR) and transfemoral (TF) access for percutaneous coronary intervention (PCI) in patients with end-stage stage renal disease (ESRD).
Methods: Online databases were queried to compare cardiovascular outcomes among TR. and TF in ESRD patients. The outcomes assessed included differences in mortality, cerebrovascular accidents (CVA), periprocedural myocardial infarction (MI), bleeding, transfusion, and periprocedural cardiogenic shock (CS). Unadjusted odds ratios (OR) were calculated using a random-effect effect model.
Results: A total of 6 studies including 7,607 patients (TR-PCI = 1,288; TF-PCI = 6,319) were included. The overall mean age was 67.7 years, while the mean age for TR-PCI and TF-PCI was 69.7 years and 67.9 years, respectively. TR-PCI was associated with lower incidence of mortality (OR 0.46 95 % CI 0.30-0.70, p < 0.05, I2 0.00 %), bleeding (OR 0.45 95 % CI 0.29, 0.68, p < 0.05, I2 3.48 %), and transfusion requirement (OR 0.52 95 % CI 0.40, 0.67, p < 0.05, I2 0.00 %) (Fig. 1). There were no differences among TR-PCI and TF-PCI for periprocedural MI, periprocedural CS, and CVA outcomes.
Conclusion: TR access was associated with lower mortality, bleeding, and transfusion requirement as compared to TF access in patients with ESRD undergoing PCI.
Recommended Citation
Sattar, Yasar; Faisaluddin, Mohammed; Almas, Talal; Alhajri, Noora; Shah, Rajendra; Zghouzi, Mohamed; Zafrullah, Fnu; Sengodon, Prasana M; Zia Khan, Muhammad; Ullah, Waqas; Alam, Mahboob; Balla, Sudharshan; Lakkis, Nasser; Kawsara, Akram; Daggubati, Ramesh; and Chadi Alraies, M, "Cardiovascular Outcomes of Transradial Versus Transfemoral Percutaneous Coronary Intervention in End-Stage Renal Disease: A Regression-Based Comparison" (2022). Division of Cardiology Faculty Papers. Paper 105.
https://jdc.jefferson.edu/cardiologyfp/105
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Language
English
PubMed ID
36051245
Comments
This article is the author's final published version in IJC Heart and Vasculature, Volume 43, December 2022, Article number 101110.
The published version is available at https://doi.org/10.1016/j.ijcha.2022.101110.
Copyright © 2022 Published by Elsevier B.V.
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).