Does Perioperative Use of Renin-Angiotensin System Inhibitors Improve Patient Outcomes in Cardiac Surgery?

Authors

Qian Ding, Tangdu Hospital
Mark Berguson, Thomas Jefferson UniversityFollow
Zugui Zhang, Christiana Care Health System
Hong Liu, UC Davis Medical Center
Huang Nie, Xijing Hospital
Jordan E. Goldhammer, Thomas Jefferson UniversityFollow
Rohinton J. Morris, Thomas Jefferson UniversityFollow
Jianzhong Sun, Thomas Jefferson UniversityFollow

Files

Description

• 2011 ACCF/AHA Guidelines for CABG: Uncertain about the safety of the preoperative administration of ACE inhibitors or ARBs in patients on chronic therapy and the safety of initiating ACE inhibitors or ARBs before hospital discharge
• 2014 ESC Guidelines: ACE inhibitors might be stopped 1 to 2 days before CABG to avoid the potential deleterious consequences of perioperative hypotension
• Guidelines state that ACE inhibitors or ARBs should be initiated postoperatively in CABG patients who were not receiving them preoperatively if they have an LVEF ≤40%, hypertension, diabetes, or CKD (Level of Evidence: A)
• There is still a lack of large clinical studies on the effects of perioperative use of RASi and long-term outcomes in cardiac surgery

Publication Date

10-19-2019

Keywords

cardiac surgery, ACE inhibitor, ARB, mortality, perioperative, renin-angiotensin system inhibitor

Disciplines

Anesthesiology | Cardiology | Medicine and Health Sciences | Surgery

Comments

Presented at Anesthesiology 2019

Document Type

Poster

Recommended Citation

Ding, Qian; Berguson, Mark; Zhang, Zugui; Liu, Hong; Nie, Huang; Goldhammer, Jordan E.; Morris, Rohinton J.; and Sun, Jianzhong, "Does Perioperative Use of Renin-Angiotensin System Inhibitors Improve Patient Outcomes in Cardiac Surgery?" (2019). Department of Anesthesiology Posters. 6.
https://jdc.jefferson.edu/anposters/6