Document Type
Report
Publication Date
12-31-2025
Abstract
Cytomegalovirus (CMV) infection has been implicated in endothelial dysfunction and atherogenesis, yet its role as a potential trigger for acute coronary syndrome (ACS) remains underrecognized. We present a case of a 32-year-old male with no prior medical history who developed non-ST elevation myocardial infarction (NSTEMI) and was subsequently found to have active CMV infection. The patient had no known history cardiovascular disease, though subsequent testing did reveal additional underlying risk factors. This case highlights the need to consider infectious etiologies, including CMV, as contributors to ACS in young, otherwise apparently healthy individuals. Understanding the interplay between viral infections and atherosclerotic disease may lead to improved risk stratification and management of patients presenting with ACS.
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.
Recommended Citation
Al Hennawi, Hussam; Sabri, Muhammad; Teng, David; Berman, Maxwell; and Shenoda, Botros, "Cytomegalovirus as a Potential Trigger for Acute Coronary Syndrome: A Case of NSTEMI in a Previously Healthy Patient" (2025). Abington Jefferson Health Papers. Paper 146.
https://jdc.jefferson.edu/abingtonfp/146
PubMed ID
41978894
Language
English

Comments
This article is the author’s final published version in Global Cardiology Science and Practice, Volume 2025, Issue 6, 2026, Pages 1-7.
The published version is available at https://doi.org/10.21542/gcsp.2025.59. Copyright © 2025 The Author(s), licensee Magdi Yacoub Institute.