Document Type

Article

Publication Date

7-26-2025

Comments

This article is the author’s final published version in American Journal of Preventive Cardiology, Volume 23, 2025, Article number 101070.

The published version is available at https://doi.org/10.1016/j.ajpc.2025.101070. Copyright © 2025 The Authors.

Abstract

Atherosclerosis, a major cause of mortality and morbidity in the United States (US), is driven by complex factors, including the cumulative burden of low-density lipoprotein cholesterol (LDL-C) and other atherogenic lipids and lipoproteins. Lipid management in US primary care aims to prevent atherosclerotic cardiovascular disease (ASCVD) events through screening and LDL-C lowering to risk-based goals. However, lipid screening and ASCVD treatment is often inadequate, with few patients meeting LDL-C goals in clinical practice. Primary care providers have a vital role in identifying patients most at risk of ASCVD to prevent ASCVD events and improve patient outcomes. There are multiple different management guidelines, risk stratification tools, tests, and management strategies available to primary care physicians. Understanding the nuances of the lipid patient and how to employ these tools can be challenging. Here, we aim to summarize what primary care providers need to know about the lipid patient and why. We review recent updates in ASCVD prevention, including the Predicting Risk of Cardiovascular Disease Events (PREVENT™) tool and nonstatin lipid-lowering therapy management approaches.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

PubMed ID

40838135

Language

English

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