From Aortic Stenosis to Cardiomyopathy: The Hidden Impact of Undiagnosed Acommissural Unicuspid Aortic Valve

Authors

Muhammad Sabri, Jefferson Abington HospitalFollow
Hamza Muhammadzai, Thomas Jefferson UniversityFollow
Angad Bedi, Jefferson Abington HospitalFollow
Eddy Mizrahi, Jefferson Abington HospitalFollow
Matthew Collins, Thomas Jefferson UniversityFollow

Document Type

Article

Publication Date

7-2-2025

Comments

This article is the author's final published version in JACC: Case Reports, Volume 30, Issue 17, July 2025, Article number 103899.

The published version is available at https://doi.org/10.1016/j.jaccas.2025.103899. Copyright © The Author(s).

Abstract

Unicuspid aortic valve (UAV) is a rare congenital anomaly, diagnosed in individuals aged 30 to 50. It is associated with aortic stenosis or aortic regurgitation, potentially leading to heart failure. We report a case of a 28-year-old male with an acommissural UAV, aortopathy, critical aortic stenosis, and heart failure with reduced ejection fraction, presenting with shortness of breath. This case is notable for late presentation of an acommissural UAV, which typically manifests in childhood.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

Recommended Citation

Sabri, Muhammad; Muhammadzai, Hamza; Bedi, Angad; Mizrahi, Eddy; and Collins, Matthew, "From Aortic Stenosis to Cardiomyopathy: The Hidden Impact of Undiagnosed Acommissural Unicuspid Aortic Valve" (2025). Abington Jefferson Health Papers. Paper 129.
https://jdc.jefferson.edu/abingtonfp/129

PubMed ID

40615215

Language

English