Leiomyosarcoma is a malignant tumor of mesenchymal cells and is the most common soft-tissue sarcoma. Leiomyosarcoma is a notably rare tumor in the ophthalmic region and can be of primary, secondary or metastatic origin. To the best of our knowledge, there has only been one published case of leiomyosarcoma metastasis to the choroid. In this case study, we report two cases of primary leiomyosarcoma with metastasis to the choroid of the eye. Both cases displayed systemic metastasis and showed response to high dose plaque radiotherapy. Despite its prevalence as the leading form of sarcoma, leiomyosarcoma rarely metastasizes to the ocular region.
Recommended CitationFeinstein, Eric; Kaliki, Swathi; Shields, Carol L; Ehya, Hormoz; and Shields, Jerry A, "Choroidal metastasis from leiomyosarcoma in two cases" (2014). Wills Eye Institute Papers. Paper 45.