Results of a Prospective Trial to Evaluate Novel Lung Function Imaging for Lung Cancer Surgery

Authors

Lydia J. Wilson, PhD, Thomas Jefferson UniversityFollow
Richard Castillo, PhD, Emory University
Edward Castillo, PhD, The University of Texas at Austin
Bernard Jones, PhD, University of Colorado
Moyed Miften, PhD, University of Colorado
Lindsey Olsen, PhD, University of Colorado
Vikas Aragam, PhD, Thomas Jefferson UniversityFollow
Robert A. Meguid, MD, MPH, University of Colorado
Crystal J. Erickson, MD, University of Colorado
Amanda Young, MSN, University of Colorado
Matthew Blum, MD, University of Colorado
Tyler Grenda, MD, Thomas Jefferson UniversityFollow
Julie Barta, MD, Thomas Jefferson UniversityFollow
Benjamin Leiby, PhD, Thomas Jefferson UniversityFollow
Timothy Waxweiler, MD, University of Colorado
Brian Kavanagh, MD, MPH, University of Colorado
John D. Mitchell, MD, University of Colorado
Yevgeniy Vinogradskiy, PhD, Thomas Jefferson UniversityFollow

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Description

Background

• Surgery is the primary form of definitive treatment for early-stage lung cancer.
• Poor lung function before surgery places patients at high risk of pulmonary complications after resection.
• Surgeons evaluate patient fitness for surgery using pulmonary function tests (PFTs) to calculate the predicted postoperative PFT (ppoPFT).
• Conventional ppoPFT calculations assume homogeneous lung function, which can be inaccurate.
• 4DCT-ventilation is a novel lung function imaging modality developed in radiation oncology that uses 4DCT data to calculate high-resolution ventilation maps.

Publication Date

8-22-2024

Keywords

lung cancer, surgery, functional imaging

Disciplines

Medicine and Health Sciences | Oncology | Pulmonology

Comments

Presented at the 2024 Department of Radiation Oncology Symposium.

Recommended Citation

Wilson, PhD, Lydia J.; Castillo, PhD, Richard; Castillo, PhD, Edward; Jones, PhD, Bernard; Miften, PhD, Moyed; Olsen, PhD, Lindsey; Aragam, PhD, Vikas; Meguid, MD, MPH, Robert A.; Erickson, MD, Crystal J.; Young, MSN, Amanda; Blum, MD, Matthew; Grenda, MD, Tyler; Barta, MD, Julie; Leiby, PhD, Benjamin; Waxweiler, MD, Timothy; Kavanagh, MD, MPH, Brian; Mitchell, MD, John D.; and Vinogradskiy, PhD, Yevgeniy, "Results of a Prospective Trial to Evaluate Novel Lung Function Imaging for Lung Cancer Surgery" (2024). Department of Radiation Oncology Posters. 2.
https://jdc.jefferson.edu/radoncposters/2