Document Type
Article
Publication Date
11-9-2016
Abstract
This paper characterizes three novel microwave applicators based on zero-order mode resonators for use in hyperthermia treatment of cancer. The radiation patterns are studied with numerical simulations in muscle tissue-equivalent model at 434 MHz. The relative performance of the applicators is compared in terms of reflection coefficient, current distribution, power deposition (SAR) pattern, effective field size in 2D and 3D tissue volumes, and penetration depth. One particular configuration generated the most uniform SAR pattern, with 25% SAR covering 84 % of the treatment volume extending to 1 cm depth under the aperture, while remaining above 58% coverage as deep as 3 cm under the aperture. Recommendations are made to further optimize this structure.
Recommended Citation
Vrba, David; Vrba, Jan; Rodrigues, Dario B.; and Stauffer, Paul R., "Numerical investigation of novel microwave applicators based on zero-order mode resonance for hyperthermia treatment of cancer" (2016). Department of Radiation Oncology Faculty Papers. Paper 83.
https://jdc.jefferson.edu/radoncfp/83
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Comments
This article has been peer reviewed. It is the authors' final version prior to publication in the Journal of the Franklin Institute.
November 2016.
The published version is available at http://dx.doi.org/10.1016/j.jfranklin.2016.10.044. Copyright © Elsevier