Document Type
Article
Publication Date
2-8-2024
Abstract
The mRNA-LNP vaccine has received much attention during the COVID-19 pandemic since it served as the basis of the most widely used SARS-CoV-2 vaccines in Western countries. Based on early clinical trial data, these vaccines were deemed safe and effective for all demographics. However, the latest data raise serious concerns about the safety and effectiveness of these vaccines. Here, we review some of the safety and efficacy concerns identified to date. We also discuss the potential mechanism of observed adverse events related to the use of these vaccines and whether they can be mitigated by alterations of this vaccine mechanism approach.
Recommended Citation
Igyártó, Botond Z. and Qin, Zhen, "The mRNA-LNP Vaccines - The Good, The Bad and The Ugly?" (2024). Department of Microbiology and Immunology Faculty Papers. Paper 184.
https://jdc.jefferson.edu/mifp/184
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
PubMed ID
38390323
Language
English
Comments
This article, first published by Frontiers Media, is the author's final published version in Frontiers in Immunology, Volume 15, 2024, Article number 1336906.
The published version is available at https://doi.org/10.3389/fimmu.2024.1336906.
Copyright © 2024 Igyártó and Qin