Psychiatric manifestations of vitamin B-12 deficiency are reviewed from 1986 to the present. Specific clinical entities reviewed include depression, organic psychosis, obsessive-compulsive disorder, childhood manifestations and dementia. We recommend that consideration be given to B-12 deficiency as an etiological factor in some cases of depression, organic psychosis, certain childhood disorders and dementia. Routine screening of people overage 65 is addressed.
Metzler, M.S., M.D., David; Miller, M.D., William H.; and Edwards, M.D., C. Stephen
"Psychiatric Manifestation of Vitamin B-12 Deficiency: An Update,"
Jefferson Journal of Psychiatry:
2, Article 8.
Available at: http://jdc.jefferson.edu/jeffjpsychiatry/vol9/iss2/8