Clorapine is an atypical antipsychotic agent associated with a higher frequency of seizures than standard neuroleptics. In addition, clozapine causes epileptiform abnormalities in the EEG in up to 72% of patients. A patient who developed a generalized seizure shortly after beginning clozapine treatment and the patient's EEG findings are presented. The neuropharmacology of dozapine and the management of clozapine-induced seizures and EEG abnormalities are discussed.
Daly, M.D., Jeffrey and Salloway, M.D., M.S., Stephen
"Clozapine-Induced Seizures and EEG Changes: A Case Report and Discussion of Clinical Management,"
Jefferson Journal of Psychiatry: Vol. 11
, Article 8.
Available at: http://jdc.jefferson.edu/jeffjpsychiatry/vol11/iss1/8